Calculating total score of a column

I have a google sheets with the following format:
A list of rows that list criteria
A list of cols per row that either have a numerical value from 1-10 or a yes/no answer (I guess could be represented as 1/0).
Question:
How can I assign weights per row so that at the bottom of each column I get a total summed score which would be the sum of weight * col_value over a column?